At Meshkati, our mission is to push the boundaries of hair restoration research. We invest in scientific innovation and advanced formulations, ensuring that each solution meets the highest standards of efficacy, safety, and precision.
Our research is grounded in four core pillars, each representing a critical area of exploration that drives our ongoing innovation and clinical excellence:
- Procedure Innovation – Advancing the Future of Hair Restoration
We invest in continuous research to improve surgical techniques and develop advanced solutions for non-invasive hair restoration. Our focus is on elevating precision, reducing downtime, and enhancing patient experience. We also explore new approaches to achieving greater hair density—whether through refined procedural methods or innovative techniques. - Epigenetics & Genetic Research – Unlocking Gene-Based Hair Regeneration
We explore how gene expression and inherited factors influence hair loss and regrowth. This includes studying epigenetic mechanisms and developing personalized, gene-responsive therapies that support long-term follicular regeneration. - Biological & Cellular Science – Understanding Scalp Aging and Follicular Health
Our research investigates the biology of scalp aging, follicular degeneration, inflammation, and cellular rejuvenation. These insights guide the development of targeted therapeutic strategies and regenerative treatments. - Formulation Research – Designing Safe & Effective Ingredient-Based Solutions
We are constantly identifying and testing highly effective active ingredients—both natural and lab-developed—with a strong emphasis on safety, synergistic performance, and scientifically validated results in hair and scalp health.
Breakthrough Innovations from Our Research
Our pioneering work at Meshkati has led to the development of exclusive solutions that redefine hair restoration—from non-surgical breakthroughs to advanced regenerative formulations.
Nanoprocedure – A Pioneering Non-Surgical Hair Restoration Solution
Developed after years of research, the Nanoprocedure is our signature non-surgical approach to hair restoration. It delivers immediate, natural-looking density through precision techniques—exclusively applied at the Meshkati Clinic in London.
FUE Procedure with Regenerative Protocol – Precision Enhanced by Science
Our refined FUE technique uses the finest tools in a minimally invasive surgical process, elevated by a proprietary protocol applied before, during, and after the procedure. This structured approach is designed to optimize graft survival, enhance density, and significantly reduce recovery time—setting a new clinical standard.
Advanced Serum (Patent Pending)
The Advanced Serum is the result of extensive research into follicular regeneration. With a potent combination of clinically selected active ingredients, this formulation is designed to stimulate hair growth, improve scalp vitality, and support long-term density.
Chemosoft – A Solution for Medically Induced Hair Loss
Chemosoft is an exclusive hair restoration solution specifically developed to address hair loss during chemotherapy or any temporary hair loss.
A Vision for the Future
Our research is continuously evolving, driven by our commitment to scientific excellence and patient-focused innovation.
1. Scalp Microenvironment Research: Enhancing Follicular Health & Longevity
Understanding Follicular Aging & Cellular Rejuvenation
The scalp microenvironment plays a crucial role in hair health. Hair follicles exist in a delicate balance, affected by inflammation, oxidative stress, microbiome imbalance, and aging-related deterioration. Research in this area helps us understand how external and internal factors impact hair follicle longevity and regrowth potential.
Key Areas of Research:
Cellular Senescence & Follicular Aging
Over time, hair follicles undergo miniaturization, leading to weaker, thinner hair growth.
We are studying anti-aging compounds and follicular stem cell activation to extend the growth phase (anagen phase) of hair.
Key areas: NAD+ boosters, stem cell-derived exosomes, and peptide therapy.
Scalp Microbiome Balance & Regeneration
The scalp has a unique microbiome, similar to the gut microbiome, which plays a role in scalp health, inflammation, and hair density.
We are testing probiotic and postbiotic scalp treatments to enhance microbial diversity and optimize follicular function.
Scalp Inflammation & Hair Loss Prevention
Chronic microinflammation of the scalp leads to fibrosis, follicle shrinkage, and eventual hair loss.
Research focuses on anti-inflammatory, bioactive plant extracts and lipid barrier repair formulations to counteract scalp stress.
Nutrient & Oxygen Supply to Follicles – Optimizing vascularization and oxygenation to enhance follicle metabolism.
Potential Innovations from This Research:
Development of scalp rejuvenation serums targeting aging follicles.
Introduction of microbiome-friendly scalp treatments to promote natural follicle regeneration.
2. Epigenetic Hair Loss Research: Unlocking Gene-Based Hair Regeneration
Exploring Gene-Based Interventions for Hair Regrowth
Why It Matters:
Hair loss is not just genetic—it is influenced by epigenetics, meaning environmental factors (stress, nutrition, toxins) turn certain genes on or off. This means even individuals without a genetic predisposition can develop hair loss.
Key Areas of Research:
Gene Expression & Hair Follicle Growth
Some genes regulate hair follicle dormancy and activation. Our research focuses on targeting gene expression through natural and synthetic compounds to prolong the growth phase (anagen phase) and delay the shedding phase (telogen phase).
We are investigating three critical biological pathways:
Wnt Signaling Activators: These helps activate dormant hair follicle stem cells and initiate the hair growth cycle. Boosting Wnt signaling can stimulate new follicle activity and promote sustained hair regeneration.
BMP Inhibitors (Bone Morphogenetic Protein): BMP signals keep follicles in a resting phase. By inhibiting this pathway, we aim to remove that suppression and allow follicles to re-enter the growth phase.
Hedgehog Pathway Regulators: This pathway plays a role in follicle development and rejuvenation. Targeted modulation can help reactivate miniaturized or aging follicles to improve density and regrowth.
DNA Methylation & Hair Loss Acceleration
DNA methylation determines whether specific genes are turned on or off. Over time, or in response to stress or environmental triggers, methylation can silence the genes that support hair growth.
We are studying natural DNA methylation modifiers—such as polyphenols, resveratrol, and adaptogens—to help maintain active gene expression and prevent premature follicular aging.
- Hormonal Epigenetics & Hair Loss
Hormonal hair loss, such as androgenetic alopecia, is linked to DHT (dihydrotestosterone) sensitivity, which is partly regulated by gene expression.
Our research focuses on non-hormonal compounds that can modulate DHT sensitivity at the gene level, without interfering with the body’s hormonal balance.
Potential Innovations:
- Epigenetic-based hair regrowth treatments targeting follicular gene expression
- Development of non-hormonal, DHT-modulating treatments for androgenetic alopecia
3. AI-Driven Hair Health Diagnostics: The Future of Personalized Hair Restoration
Developing Personalised Scalp Analysis Tools for Tailored Treatments
Why It Matters:
Most hair loss treatments follow a one-size-fits-all approach, yet hair loss patterns and scalp conditions vary dramatically. AI-driven diagnostics allow for precise, customized treatment plans based on real-time scalp data.
Key Areas of Research:
AI-Powered Scalp & Hair Follicle Analysis
Machine learning models can analyze scalp conditions, detect early-stage follicular miniaturization, and predict hair loss trends before they become visible.
Research focuses on developing an AI scalp scanner that can classify oil levels, follicular density, scalp inflammation, and genetic predisposition.
Predictive Modelling for Hair Loss Progression
AI can track hair loss progression over time, creating personalized regrowth timelines.
Patients receive adaptive treatment recommendations based on how their follicles respond to their treatment.
Personalized Treatment Algorithms
AI can match patients with the most effective formulations and regimens based on their specific scalp and hair profile.
The system would continuously refine treatment plans based on scalp response, improving outcomes over time.
Potential Innovations from This Research:
- AI-powered scalp analysis app for real-time hair loss diagnostics.
- Personalized, data-driven treatment recommendations for optimal regrowth strategies.